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Welcome! We are located on the 3rd floor of the Genome Sciences Building at the University of North Carolina, Chapel Hill, NC.

Our research interests broadly span population genetics, statistical inference, and evolutionary genomics. We are interested in how nonadaptive evolutionary processes like changes in population size, recombination, mutation, direct and indirect effects of negative selection and factors such as genome architecture jointly shape patterns of genomic variation. Work in the lab involves employing computational and theoretical approaches, developing statistical methods, or using an empirical approach to perform evolutionary inference and ask fundamental questions in population genetics. To learn more, please check our Research page. Here are some questions that we are interested in:

  • How much do adaptive vs. non-adaptive evolutionary processes contribute to genome-wide patterns of variation?

  • How does selection against deleterious mutations shape variation at linked sites? 

  • What does the distribution of fitness effects of new mutations look like across species? How can we infer its shape from population-genetic data?

  • What are the selective forces acting on other types of mutations like gene duplicates?

NEWS

May 15, 2023        Jacob Marsh has joined us in Chapel Hill! Welcome Jacob!

May 08, 2023        Austin Daigle has officially joined the lab! Welcome Austin!

 

Apr 17, 2023         Parul gave a talk at the workshop entitled "Biological evolution across scales:                                            mathematical modelling and statistical inference", organized by EPFL. We thank the                                  organizers for the invitation! 

 

Mar 08, 2023        Parul gave a talk at the PopSim satellite meeting held at CSHL. We thank the     

                             organizers for the fantastic conference and the invitation!

 

Jan 31, 2023        We are very excited to welcome the first rotation student, Austin Daigle, to the lab!

 

 

Jan 03, 2023        Officially the first day of the lab!

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